동충하초연구 27

Phylogenetic classification of Cordyceps and the clavicipitaceous fungi

Cordyceps, comprising over 400 species, was historically classified in the Clavicipitaceae, based on cylindrical asci, thickened ascus apices and filiform ascospores, which often disarticulate into part-spores. Cordyceps was characterized by the production of welldeveloped often stipitate stromata and an ecology as a pathogen of arthropods and Elaphomyces with infrageneric classifications empha..

A multi-gene phylogeny of Clavicipitaceae (Ascomycota, Fungi)

Multi-gene phylogenetic analyses were conducted to address the evolution of Clavicipitaceae (Ascomycota). Data are presented here for approximately 5900 base pairs from portions of seven loci: the nuclear ribosomal small and large subunit DNA (nrSSU and nrLSU), b-tubulin, elongation factor 1a (EF-1a), the largest and second largest subunits of RNA polymerase II (RPB1 and RPB2), and mitochondria..

Phylogenetic evidence for an animal pathogen origin

Grass-associated fungi (grass symbionts) in the family Clavicipitaceae (Ascomycota, Hypocreales) are species whose host range is restricted to the plant family Poaceae and rarely Cyperaceae. The best-characterized species include Claviceps purpurea (ergot of rye) and Neotyphodium coenophialum (endophyte of tall fescue). They have been the focus of considerable research due to their importance i..

Cordycepin inhibits lipopolysaccharide-induced inflammation

Cordyceps militaris, a caterpillar-grown traditional medicinal mushroom, produces an important bioactive compound, cordycepin (3′-deoxyadenosine). Cordycepin is reported to possess many pharmacological activities including immunological stimulating, anti-cancer, anti-virus and anti-infection activities. The molecular mechanisms of cordycepin on pharmacological and biochemical actions of macro..

p38-Targeted inhibition of interleukin-12 expression by C. bassiana

Cordyceps species have been known as ethnopharmacologically valuable mushroom in Korea, China, and Japan. This plant has been reported to exhibit a variety of pharmacological activities such as antioxidative, anticancer, anti-inflammatory, antidiabetic, and antiobesity effects. Although numerous pharmacological potentials of Cordyceps spp. have been demonstrated, immunomodulatory effect of Cord..

Cordycepin inhibits vascular smooth muscle cell proliferation

Percutaneous transluminal coronary angioplasty (PTCA) is a common procedure for treating atherosclerosis, but its efficacy is limited because of the occurrence of restenosis within 3–6 months after angioplasty. Restenosis is induced by the remodeling of the vessel wall and/or the accumulation of cells and extracellular matrix (ECM) in the intimal layer. Therefore, the matrix metalloproteinase..

노랑다발동충하초가 아토피 효과를 외국잡지에 게재하였다.

Journal of Ethnopharmacology에 Inhibition of 2,4-dinitrofluorobenzene-induced atopic dermatitis by topical application of the butanol extract of Cordyceps bassiana in NC/Nga mice이라는 제목으로 게재하여 노랑다발동충하초가 아토피에 효과가 있는 것으로 인정을 받았다. 이제 노랑다발동충하초는 국내에서는 특허와 함께 외국 유명한 저널..